Road trip from St. Louis to Winston-Salem
All Category
Outdoor Activities
Museums
Concerts & Shows
Food & Drink
Sights & Landmarks
Shopping
All Category
Outdoor Activities
Museums
Concerts & Shows
Food & Drink
Sights & Landmarks
Shopping
Reset
Show less
ITINERARY
13h 14m702 miles8 stops
1
Willard Library
2
Waveland State Historic Site
Experience 19th century plantation life at this historic compound where you can tour the mansion or "big house," see quarters where slaves lived, visit a smokehouse and other elements of daily life in the Old South.
3
Fayette Mall
Fayette Mall is located at the intersection of Nicholasville Road and Reynolds Road. The mall is central Kentucky’s premier shopping destination with over 170 retailer and dining options including The Disney Store, H&M, Michael Kors, Sephora and The Cheesecake Factory. Fayette Mall also features a children’s play area located in Center Court. Mobile device charging stations can be found in the Food Court. WiFi is available at Starbucks, Dillard’s and Dick’s Sporting Goods. Customer Service Center is located inside the front entrance next to P.F. Chang’s. Visit shopfayette-mall.com for more information including a complete list of retailers, restaurants, entertainment options and a mall map.
4
Lexington Brewing & Distilling Co.
The first era of the Lexington Brewing Co. began in the 1890s and came to a halt during Prohibition, changing ownership several times in the decades that followed. By the time Pearse Lyons and his son, Mark, explored the brewery in 1999, it was a dilapidated shell of what it had once been. However, Pearse was a visionary and entrepreneur and saw only what it could be. Spurred by a passion for brewing and distilling that courses through the Lyons family lineage of Irish coopers, Pearse revived Lexington Brewing Co. and restored a craft beer tradition that dates back to the 1700s. Pearse continued to dream big as he set his sights on distilling — a natural progression given his background in fermentation, his family’s heritage and Kentucky’s bourbon tradition. Two copper pot stills that were commissioned from Scotland arrived at Lexington Brewing Co. in 2008. In 2012, Town Branch Distillery opened, first new distillery to be built in Lexington, Kentucky, in more than 100 yrs.
5
Iron Heart Winery
6
Grand 18-Winston-Salem
7
Lam Museum of Anthropology, Wake Forest University
Discover North Carolina's only museum dedicated to the study of global cultures. Explore stories of humanity, from ancient archaeological sites to the celebrations and struggles of today. Learn about peoples around the world through their everyday and ceremonial objects, and visual arts. Changing exhibits highlight the Museum's collections of nearly 30,000 archaeological and ethnographic artifacts from more than 350 cultures and 90 countries. Admission is free.
8
Salem Lake
Customize this Trip
OVERVIEW
1
Start:Willard Library
Evansville, Indiana·
4.5
(97) review
21 N 1st Ave, Evansville, IN 47710-1294
2
Start:Waveland State Historic Site
Lexington, Kentucky·
4.5
(97) review
Experience 19th century plantation life at this historic compound where you can tour the mansion or "big house," see quarters where slaves lived, visit a smokehouse and other elements of daily life in the Old South.
3
Start:Fayette Mall
Lexington, Kentucky·
4.5
(91) review
Fayette Mall is located at the intersection of Nicholasville Road and Reynolds Road. The mall is central Kentucky’s premier shopping destination with over 170 retailer and dining options including The Disney Store, H&M, Michael Kors, Sephora and The Cheesecake Factory. Fayette Mall also features a children’s play area located in Center Court. Mobile device charging stations can be found in the Food Court. WiFi is available at Starbucks, Dillard’s and Dick’s Sporting Goods. Customer Service Center is located inside the front entrance next to P.F. Chang’s. Visit shopfayette-mall.com for more information including a complete list of retailers, restaurants, entertainment options and a mall map.
4
Start:Lexington Brewing & Distilling Co.
Lexington, Kentucky·
4.5
(984) review
The first era of the Lexington Brewing Co. began in the 1890s and came to a halt during Prohibition, changing ownership several times in the decades that followed. By the time Pearse Lyons and his son, Mark, explored the brewery in 1999, it was a dilapidated shell of what it had once been. However, Pearse was a visionary and entrepreneur and saw only what it could be. Spurred by a passion for brewing and distilling that courses through the Lyons family lineage of Irish coopers, Pearse revived Lexington Brewing Co. and restored a craft beer tradition that dates back to the 1700s. Pearse continued to dream big as he set his sights on distilling — a natural progression given his background in fermentation, his family’s heritage and Kentucky’s bourbon tradition. Two copper pot stills that were commissioned from Scotland arrived at Lexington Brewing Co. in 2008. In 2012, Town Branch Distillery opened, first new distillery to be built in Lexington, Kentucky, in more than 100 yrs.
5
Start:Iron Heart Winery
Allisonia, Virginia·
4.0
(7) review
3742 Boone Furnace Rd, Allisonia, VA 24347-4001
6
Start:Grand 18-Winston-Salem
Winston Salem, North Carolina·
4.0
(72) review
5601 University Pkwy, Winston Salem, NC 27105-1313
7
Start:Lam Museum of Anthropology, Wake Forest University
Winston Salem, North Carolina·
4.0
(9) review
Discover North Carolina's only museum dedicated to the study of global cultures. Explore stories of humanity, from ancient archaeological sites to the celebrations and struggles of today. Learn about peoples around the world through their everyday and ceremonial objects, and visual arts. Changing exhibits highlight the Museum's collections of nearly 30,000 archaeological and ethnographic artifacts from more than 350 cultures and 90 countries. Admission is free.
8
Start:Salem Lake
Winston Salem, North Carolina·
4.5
(97) review
1001 Salem Lake Rd, Winston Salem, NC 27107-1571
CHECKLIST
GPS device or app
Download Offline Map
Car charger and portable battery
Water bottles and snacks
Travel pillow and blanket
Sunglasses and sunscreen
First-aid kit
Trash bags
Hand sanitizer and wet wipes
Driver’s license and vehicle registration
Cash and cards
Camera or smartphone
Unlock Effortless Travel Planning
Create your dream trip in minutes by this prompt. Try now!
EXPLORE MORE
Discover Exciting Road Trip Inspirations
St. Louis to Portland
2,044 miles
35h 24m
30 stops
MuseumsNature & ParksToursFun & GamesNightlife
St. Louis to Orlando
998 miles
18h 22m
24 stops
Sights & LandmarksToursShoppingNature & ParksMuseums
St. Louis to Riverside
1,791 miles
31h 5m
22 stops
Outdoor ActivitiesMuseumsNature & ParksSights & LandmarksTours
St. Louis to Sacramento
1,969 miles
33h 49m
24 stops
Water & Amusement ParksMuseumsNature & ParksToursFun & Games
St. Louis to Cincinnati
350 miles
6h 37m
22 stops
Fun & GamesMuseumsToursSights & LandmarksNightlife
St. Louis to San Antonio
900 miles
16h 39m
24 stops
NightlifeFun & GamesShoppingTraveler ResourcesConcerts & Shows
EXPLORE OTHER
Check Out Different Road Trip Options
Portland to Huntington
2,938 miles
51h 56m
39 stops
Fun & GamesNature & ParksFood & DrinkToursNightlife
Arlington to St. Petersburg
1,111 miles
21h 1m
19 stops
ToursOutdoor ActivitiesShoppingNature & ParksConcerts & Shows
Henderson to Chandler
304 miles
6h 14m
20 stops
Outdoor ActivitiesNature & ParksMuseumsSights & LandmarksEvents
McAllen to Trenton
1,937 miles
36h 0m
44 stops
ShoppingSpas & WellnessNature & ParksFun & GamesSights & Landmarks
San Francisco to Huntsville
2,305 miles
41h 4m
35 stops
ToursFun & GamesOutdoor ActivitiesNature & ParksSights & Landmarks
Champaign to High Point
655 miles
12h 41m
23 stops
Outdoor ActivitiesFun & GamesNightlifeMuseumsConcerts & Shows
FAQ
Frequently Asked Questions
What's the driving distance between St. Louis and Winston-Salem?
The distance is 702 miles
What's the travel time between St. Louis and Winston-Salem?
The driving time can vary depending on traffic conditions, but it is typically 13h 14m mins in normal traffic
What are some of the best cities to visit between St. Louis and Winston-Salem?
Some popular stops include
Are there any cool sights or attractions I shouldn't miss on my drive to Winston-Salem?
There are plenty! Here are some stops you shouldn’t miss on your way to Winston-Salem
What’s the weather like in Winston-Salem?
The weather in Winston-Salem is generally mild year-round, with warm, dry summers and cool, wet winters. See the links below for more information
Weather in Winston-Salem in January
Weather in Winston-Salem in February
Weather in Winston-Salem in March
Weather in Winston-Salem in April
Weather in Winston-Salem in May
Weather in Winston-Salem in June
Weather in Winston-Salem in July
Weather in Winston-Salem in August
Weather in Winston-Salem in September
Weather in Winston-Salem in October
Weather in Winston-Salem in November
Weather in Winston-Salem in December
Interested in a detailed plan for your time in Winston-Salem?
Plan your dream Winston-Salem trip with our daily itineraries featuring must-see attractions! See them here!
A 1-day itinerary in Winston-Salem
A 2-day itinerary in Winston-Salem
A 3-day itinerary in Winston-Salem
A 4-day itinerary in Winston-Salem
A 5-day itinerary in Winston-Salem
A 6-day itinerary in Winston-Salem
Where else can I travel to if I'm starting my trip in St. Louis?
We have a lot of great trip options for St. Louis! See the links below for all the itineraries we created for you