Road trip from Knoxville to Lafayette
All Category
Food & Drink
Nature & Parks
Museums
Nightlife
Fun & Games
Sights & Landmarks
Spas & Wellness
Show more (4+)
All Category
Food & Drink
Nature & Parks
Museums
Nightlife
Fun & Games
Sights & Landmarks
Spas & Wellness
Shopping
Zoos & Aquariums
Concerts & Shows
Reset
Show less
ITINERARY
13h 6m710 miles20 stops
1
The Mill and Mine
2
Peter Kern Library
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
3
Krutch Park
4
Knoxville Botanical Garden
5
Muse Knoxville
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
6
Cathedral of the Most Sacred Heart of Jesus
7
The Spice & Tea Exchange of Chattanooga
Come In and Smell the Spices! The Spice & Tea Exchange® offers food lovers, chefs, and tea enthusiasts a unique shopping experience filled with culinary delights. Explore your inner chef and shop over 140 fine spices, 75+ hand-mixed seasoning blends, sugars, salts, loose-leaf teas, and accessories. Create your own gourmet gift, or choose from a variety of gift boxes and recipe samplers!
8
Chattanooga Zoo
Imagine a zoo that's specially designed to bring the animals up close to you. Imagine a zoo where you have time to notice the subtleties of animal behavior, instead of being pushed along by an impatient crowd. Imagine an exciting and diverse zoo that's still easy to navigate with strollers...or little legs. That's the new Chattanooga Zoo!
9
River Gallery
Craft and art collections.
10
Statue of Liberty Replica
Bronze replica measuring one-fifth the size of its sister statue located in New York City.
11
McWane Science Center
Fun and learning never end at McWane Science Center, a nonprofit, hands-on museum and IMAX(R) Dome Theater. Four floors of interactive exhibits celebrate science and wonder - from an amazing collection of dinosaurs to innovative environmental showcases, imaginative early childhood playgrounds, and an awe-inspiring aquarium. The energy and excitement of discovery spring to life through an extensive lineup of science demonstrations performed daily by talented educators. The adventure intensifies in the IMAX(R) Dome Theater, where wide-eyed visitors experience the sights and sounds of breathtaking films on a 5-story-tall screen surrounded by 3 tons of high-intensity speakers.
12
Palm Court Jazz Cafe
A stylish jazz spot in the French Quarter, which serves Cajun and Creole dishes.
13
The Presbytere
The Presbytere was designed in 1791 to match the Cabildo, alongside St. Louis Cathedral in the French Quarter. It stands today as a beautiful reminder of both Louisiana's singular past and its vibrant present.The Presbytere, originally called Casa Curial or "Ecclesiastical House," was built on the site of the residence, or presbytere, of the Capuchin monks. The building was used for commercial purposes until 1834 when it became a courthouse. In 1911, it became part of the Louisiana State Museum. Two exhibitions are on display-"Living with Hurricanes: Katrina and Beyond" tells of rescue, rebuilding and renewal, and "Mardi Gras: It's Carnival Time in Louisiana" captures the fun and fantasy of the annual celebration.
14
New Orleans School of Cooking
We teach the basics of Louisiana Cooking in a way you’ll never forget. Fun is a primary ingredient in our kitchen! Our Cajun / Creole experts teach New Orleans specialties such as Gumbo, Jambalaya and Pralines, seasoning them with history, trivia and tall tales! We offer demonstration classes and hands-on classes daily! DEMONSTRATION CLASS: Watch, learn & eat! Sit back and enjoy watching our skilled, entertaining chefs prepare a classic Cajun / Creole meal for you while learning about the vibrant history of New Orleans cuisine - enjoy all the demonstrated items, as well as local Abita beer with your meal! HANDS ON CLASS: Cook & eat an authentic Louisiana meal! In this highly interactive class, our guests prepare a complete dinner with one of our expert chefs, and afterwards they are able to sit down and enjoy the meal they have just created. Served with red & white wine.
15
Jean Lafitte National Historical Park and Preserve
Nature reserve, consisting of several sections, preserves significant examples of the natural and cultural resources of the Mississippi Delta region.
16
The Courtyard Brewery
New Orleans' first nanobrewery serves handcrafted, small-batch beers made on site as well as specialty draught from around the world.
17
Vermilionville
Get a taste of life for the 18th-century Acadian settlers in this 23-acre village with meticulously recreated period homes, costumed staff demonstrating arts and crafts and a restaurant serving Cajun and Creole food.
18
Lafayette Science Museum
Step into the vibrant world of the University of Louisiana at Lafayette Science Museum, where curiosity knows no bounds!
19
Urns of Justice
20
Girard Park Center
Customize this Trip
OVERVIEW
1
Start:The Mill and Mine
Knoxville, Tennessee·
5.0
(9) review
227 W Depot Ave, Knoxville, TN 37917-7521
2
Start:Peter Kern Library
Knoxville, Tennessee·
4.0
(99) review
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
3
Start:Krutch Park
Knoxville, Tennessee·
4.5
(90) review
504 Market St, Knoxville, TN 37902-2107
4
Start:Knoxville Botanical Garden
Knoxville, Tennessee·
3.5
(97) review
2743 Wimpole Ave, Knoxville, TN 37914-5958
5
Start:Muse Knoxville
Knoxville, Tennessee·
4.0
(91) review
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
6
Start:Cathedral of the Most Sacred Heart of Jesus
Knoxville, Tennessee·
4.5
(9) review
711 S Northshore Dr, Knoxville, TN 37919-7593
7
Start:The Spice & Tea Exchange of Chattanooga
Chattanooga, Tennessee·
5.0
(92) review
Come In and Smell the Spices! The Spice & Tea Exchange® offers food lovers, chefs, and tea enthusiasts a unique shopping experience filled with culinary delights. Explore your inner chef and shop over 140 fine spices, 75+ hand-mixed seasoning blends, sugars, salts, loose-leaf teas, and accessories. Create your own gourmet gift, or choose from a variety of gift boxes and recipe samplers!
8
Start:Chattanooga Zoo
Chattanooga, Tennessee·
4.0
(907) review
Imagine a zoo that's specially designed to bring the animals up close to you. Imagine a zoo where you have time to notice the subtleties of animal behavior, instead of being pushed along by an impatient crowd. Imagine an exciting and diverse zoo that's still easy to navigate with strollers...or little legs. That's the new Chattanooga Zoo!
9
Start:River Gallery
Chattanooga, Tennessee·
4.5
(98) review
Craft and art collections.
10
Start:Statue of Liberty Replica
Birmingham, Alabama·
4.0
(97) review
Bronze replica measuring one-fifth the size of its sister statue located in New York City.
11
Start:McWane Science Center
Birmingham, Alabama·
4.5
(963) review
Fun and learning never end at McWane Science Center, a nonprofit, hands-on museum and IMAX(R) Dome Theater. Four floors of interactive exhibits celebrate science and wonder - from an amazing collection of dinosaurs to innovative environmental showcases, imaginative early childhood playgrounds, and an awe-inspiring aquarium. The energy and excitement of discovery spring to life through an extensive lineup of science demonstrations performed daily by talented educators. The adventure intensifies in the IMAX(R) Dome Theater, where wide-eyed visitors experience the sights and sounds of breathtaking films on a 5-story-tall screen surrounded by 3 tons of high-intensity speakers.
12
Start:Palm Court Jazz Cafe
New Orleans, Louisiana·
4.5
(99) review
A stylish jazz spot in the French Quarter, which serves Cajun and Creole dishes.
13
Start:The Presbytere
New Orleans, Louisiana·
4.5
(999) review
The Presbytere was designed in 1791 to match the Cabildo, alongside St. Louis Cathedral in the French Quarter. It stands today as a beautiful reminder of both Louisiana's singular past and its vibrant present.The Presbytere, originally called Casa Curial or "Ecclesiastical House," was built on the site of the residence, or presbytere, of the Capuchin monks. The building was used for commercial purposes until 1834 when it became a courthouse. In 1911, it became part of the Louisiana State Museum. Two exhibitions are on display-"Living with Hurricanes: Katrina and Beyond" tells of rescue, rebuilding and renewal, and "Mardi Gras: It's Carnival Time in Louisiana" captures the fun and fantasy of the annual celebration.
14
Start:New Orleans School of Cooking
New Orleans, Louisiana·
5.0
(9878) review
We teach the basics of Louisiana Cooking in a way you’ll never forget. Fun is a primary ingredient in our kitchen! Our Cajun / Creole experts teach New Orleans specialties such as Gumbo, Jambalaya and Pralines, seasoning them with history, trivia and tall tales! We offer demonstration classes and hands-on classes daily! DEMONSTRATION CLASS: Watch, learn & eat! Sit back and enjoy watching our skilled, entertaining chefs prepare a classic Cajun / Creole meal for you while learning about the vibrant history of New Orleans cuisine - enjoy all the demonstrated items, as well as local Abita beer with your meal! HANDS ON CLASS: Cook & eat an authentic Louisiana meal! In this highly interactive class, our guests prepare a complete dinner with one of our expert chefs, and afterwards they are able to sit down and enjoy the meal they have just created. Served with red & white wine.
15
Start:Jean Lafitte National Historical Park and Preserve
New Orleans, Louisiana·
4.5
(999) review
Nature reserve, consisting of several sections, preserves significant examples of the natural and cultural resources of the Mississippi Delta region.
16
Start:The Courtyard Brewery
New Orleans, Louisiana·
4.5
(98) review
New Orleans' first nanobrewery serves handcrafted, small-batch beers made on site as well as specialty draught from around the world.
17
Start:Vermilionville
Lafayette, Lafayette Parish, Louisiana·
4.5
(880) review
Get a taste of life for the 18th-century Acadian settlers in this 23-acre village with meticulously recreated period homes, costumed staff demonstrating arts and crafts and a restaurant serving Cajun and Creole food.
18
Start:Lafayette Science Museum
Lafayette, Lafayette Parish, Louisiana·
4.5
(96) review
Step into the vibrant world of the University of Louisiana at Lafayette Science Museum, where curiosity knows no bounds!
19
Start:Urns of Justice
Lafayette, Lafayette Parish, Louisiana·
3.5
(9) review
800 Lafayette St in front of John M. Shaw US Courthouse, Lafayette, LA 70501-6800
20
Start:Girard Park Center
Lafayette, Lafayette Parish, Louisiana·
4.0
(8) review
500 Girard Park Dr, Lafayette, LA 70503-2623
CHECKLIST
GPS device or app
Download Offline Map
Car charger and portable battery
Water bottles and snacks
Travel pillow and blanket
Sunglasses and sunscreen
First-aid kit
Trash bags
Hand sanitizer and wet wipes
Driver’s license and vehicle registration
Cash and cards
Camera or smartphone
Unlock Effortless Travel Planning
Create your dream trip in minutes by this prompt. Try now!
EXPLORE MORE
Discover Exciting Road Trip Inspirations
Knoxville to Baton Rouge
650 miles
11h 54m
31 stops
Food & DrinkNature & ParksToursMuseumsNightlife
Knoxville to Albany
828 miles
15h 45m
36 stops
ToursSights & LandmarksNature & ParksNightlifeMuseums
Knoxville to Grand Rapids
578 miles
11h 17m
18 stops
NightlifeNature & ParksMuseumsSights & LandmarksFood & Drink
Knoxville to Ogden
1,799 miles
31h 45m
23 stops
NightlifeNature & ParksMuseumsSights & LandmarksTours
Knoxville to New Haven
785 miles
15h 7m
25 stops
ToursSights & LandmarksNature & ParksNightlifeMuseums
Knoxville to Bakersfield
2,201 miles
38h 32m
25 stops
ToursFun & GamesOutdoor ActivitiesNature & ParksConcerts & Shows
EXPLORE OTHER
Check Out Different Road Trip Options
Queens to Hayward
2,936 miles
51h 41m
36 stops
Sights & LandmarksNature & ParksWater & Amusement ParksMuseumsFun & Games
Greenville to Muskegon
765 miles
15h 16m
28 stops
Outdoor ActivitiesShoppingSights & LandmarksNightlifeNature & Parks
Richmond to Spring Hill
773 miles
14h 43m
32 stops
Nature & ParksFun & GamesOutdoor ActivitiesOtherConcerts & Shows
Durham to Hagerstown
322 miles
6h 18m
23 stops
Fun & GamesConcerts & ShowsShoppingOutdoor ActivitiesSights & Landmarks
New Orleans to Asheville
653 miles
12h 29m
14 stops
Nature & ParksMuseumsConcerts & ShowsToursBoat Tours & Water Sports
McAllen to Laredo
149 miles
3h 1m
14 stops
ShoppingSpas & WellnessConcerts & ShowsNature & ParksMuseums
FAQ
Frequently Asked Questions
What's the driving distance between Knoxville and Lafayette?
The distance is 710 miles
What's the travel time between Knoxville and Lafayette?
The driving time can vary depending on traffic conditions, but it is typically 13h 6m mins in normal traffic
What are some of the best cities to visit between Knoxville and Lafayette?
Some popular stops include
Are there any cool sights or attractions I shouldn't miss on my drive to Lafayette?
There are plenty! Here are some stops you shouldn’t miss on your way to Lafayette
What’s the weather like in Lafayette?
The weather in Lafayette is generally mild year-round, with warm, dry summers and cool, wet winters. See the links below for more information
Weather in Lafayette in January
Weather in Lafayette in February
Weather in Lafayette in March
Weather in Lafayette in April
Weather in Lafayette in May
Weather in Lafayette in June
Weather in Lafayette in July
Weather in Lafayette in August
Weather in Lafayette in September
Weather in Lafayette in October
Weather in Lafayette in November
Weather in Lafayette in December
Interested in a detailed plan for your time in Lafayette?
Plan your dream Lafayette trip with our daily itineraries featuring must-see attractions! See them here!
A 1-day itinerary in Lafayette
A 2-day itinerary in Lafayette
A 3-day itinerary in Lafayette
A 4-day itinerary in Lafayette
A 5-day itinerary in Lafayette
A 6-day itinerary in Lafayette
Where else can I travel to if I'm starting my trip in Knoxville?
We have a lot of great trip options for Knoxville! See the links below for all the itineraries we created for you